Science Daily  September 15, 2022 To evaluate the impact of mutations on 17 antibodies used in 11 commercially available antigen tests with emergency use authorization a team of researchers in the US (Emory University, Baylor College, industry) measured antibody binding for all possible Nucleocapsid point mutations using a mammalian surface-display platform and deep mutational scanning. The results provided a complete map of the antibodies’ epitopes and their susceptibility to mutational escape. Their data predicted no vulnerabilities for detection of mutations found in variants of concern. They confirmed this using the commercial tests and sequence-confirmed COVID-19 patient samples. The antibody escapes […]