No more annual flu shot? New target for universal influenza vaccine

Science Daily  December 22, 2021 An international team of researchers (USA – University of Chicago, The Scripps Research Institute, La Jolla, CA, Icahn School of Medicine at Mount Sinai, New York, Fred Hutchinson Cancer Research Center, Seattle, WA, University of Washington, University of Maryland, Austria) has found a distinct class of broadly neutralizing antibodies (bnAbs) targeting a discrete membrane-proximal anchor epitope of the hemagglutinin (HA) stalk domain. The antibodies are broadly neutralizing across H1 viruses and can cross-react with pandemic-threat H2 and H5 viruses. Anchor epitope-targeting B cells are common in the human memory B cell (MBC) repertoire and were […]