SciTech Daily  April 25, 2021 Previously an international team of researchers (USA – Florida State University, Emory University, University of Georgia, University of Illinois, Sloan Kettering Cancer Center, UK, Japan, Hong Kong) showed that each type of cell had a unique replication timing program and that diseased cells had distinct alterations in the program. In the current study, the team looked at how changes in the replication timing program impact the epigenome. They found that by eliminating a protein called RIF1, that helps to regulate DNA replication, the replication program was severely and sometimes, almost completely gone so that all […]