Marriage of synthetic biology and 3D printing produces programmable living materials

Phys.org  May 1, 2024
An international team of researchers (UK, China) integrated biocompatible hydrogel microparticles (HMPs) primed for 3D bioprinting with Agrobacterium tumefaciens capable of plant cell transfection, serving as the backbone for the simultaneous growth and transformation of tobacco BY-2 cells. The system facilitated the concurrent growth and genetic modification of tobacco BY-2 cells within their specially designed scaffolds which enabled the cells to develop into predefined patterns while remaining conducive to the uptake of exogenous DNA. The patterns developed through the integration of the betalain biosynthetic pathway into tobacco BY-2 cells. According to the researchers their work opens avenues for the evolution of sustainable, adaptive, and responsive living material systems… read more. Open Access TECHNICAL ARTICLE

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