Using electricity to increase the amount of data that can be stored by DNA

Phys.org  January 12, 2021
Researchers at Columbia University have developed a new electrogenetic framework for direct storage of digital data in living cells. Using an engineered redox-responsive CRISPR adaptation system, they encoded binary data in 3-bit units into CRISPR arrays of bacterial cells by electrical stimulation. They demonstrated multiplex data encoding into barcoded cell populations to yield meaningful information storage and capacity up to 72 bits, which can be maintained over many generations in natural open environments. Their work establishes a direct digital-to-biological data storage framework and advances the capacity for information exchange between silicon- and carbon-based entities…read more. TECHNICAL ARTICLE 

Direct digital-to-biological data storage into CRISPR arrays. Credit: Nature Chemical Biology (2021)

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