Science Daily September 14, 2021 The reactions in DNA-based combinational logic computing are mostly achieved through a manual process. For DNA-based Boolean logic, researchers in South Korea have fabricated a DNA-based microfluidic processing unit (MPU). They cast polydimethylsiloxane using double-sided molding techniques for alignment between the microfluidics and valve switch. For a uniform surface, molds fabricated using a three-dimensional printer were spin-coated by a polymer. For programming control, the valve switch arms were operated by servo motors. In the MPU controlled via a personal computer or smartphone application, the molecules with two input DNAs and a logic template DNA were […]
Tag Archives: DNA computing
DNA circuits
EurekAlert June 2, 2021 Researchers in China have developed a configurable, multi-mode logic switching network that reacts differently with its surroundings depending on pH and DNA input. They developed a series of four DNA switches, each with slightly different lengths and combinations of bases. At a slightly alkaline pH of 8, two of the switches formed triple-stranded DNA, while the others remained loosely stretched out. These reactions and folds led to secondary reactions, which were utilized by the researchers as logic functions in the switching circuit. In demonstration DNA acted as a crosslinker, joining the polymer molecules in the gel […]