Science Alert April 8, 2023
While dielectrophoretic (DEP)-based cargo manipulation can be achieved at high-solution conductivity, electrical propulsion of these micromotors becomes ineffective at solution conductivities. Researchers in Israel found that combination of a rotating magnetic field and electric field results in enhanced micromotor mobility and steering control through tuning of the electric field frequency. They demonstrated the micromotor’s ability of identifying apoptotic cell among viable and necrotic cells based on their dielectrophoretic difference. This enabled analysis of apoptotic status in the single-cell samples for drug discovery, cell therapeutics, and immunotherapy. According to the researcher’s hybrid micromotor approach for label-free trapping, transporting, and sensing of selected cells within conductive solutions opens new opportunities in drug delivery and single-cell analysis, where close-to-physiological media conditions are necessary… read more. Open Access TECHNICAL ARTICLE
CAPTION: JP propulsion and steering using a rotating magnetic field… Credit: Advanced Science, 11 December 2022