Science Daily January 19, 2023
Researchers in Japan designed and developed three new peptides for graphene biosensors that can detect odor molecules to perform two main functions — acting as a biomolecular scaffold for self-assembly on a graphene surface and functioning as a bio-probe to bind the odor molecules. They showed that the peptides uniformly covered the graphene surface with the thickness of a single molecule. When representative odor molecules were injected into the functionalized graphene field-effect transistors (GFETs), graphene conductivity reduced indicating the binding of the odor molecules. The odor molecules gave rise to distinct signatures confirming that the GFET’s response to the odor molecules depended on the peptide design. The observations also indicated that the time constraint associated with the adsorption and desorption of odor molecules was unique for each of the peptide sequences. According to the researchers their approach in simple, and can be scaled up for mass production…read more. Open Access TECHNICAL ARTICLE
Co-self-assembled structure of peptides… Credit: Biosensors and Bioelectronics, Volume 224, 15 March 2023, 115047Â