Nanowerk October 20, 2022
An international team of researchers (Japan, France) has pioneered the application of a new method that harnesses enzymes, offering initial clues as to how these technical obstacles may be overcome. They made use of the reactions of three enzymes to design chemical “neurons” that reproduce the network architecture and have the ability for complex calculations exhibited by true neurons. Their chemical neurons can execute calculations with data on DNA strands and express the results as fluorescent signals. They have also innovated by assembling two layers of the artificial neurons to refine calculations. Precision was further enhanced through microfluidic miniaturization of reactions, allowing tens of thousands to take place. These breakthroughs may eventually permit better screening for certain diseases as well as the manipulation of gigantic DNA-encoded databases...read more. TECHNICAL ARTICLEÂ
Architecture of DNA-encoded enzymatic neural networks. Credit: Nature volume 610, pages 496–501 (2022)Â