Phys.org June 29, 2021
Injectable vaccines are designed to bolster antibodies in the blood, but those antibodies are not as prevalent at the sites where infection begins. Researchers in Canada found that neutrophils, the most abundant white blood cells in the human body, explode when they bind to pathogens coated in antibodies and release DNA outside of the cell, creating a sticky tangle which acts as a trap. Mechanisms that can stop the infection at the site where it enters our body can prevent the spread and serious complications. According to the researchers we should be thinking carefully about next generation COVID-19 vaccines that could be administered in the respiratory tract to stimulate antibodies. We do not have many candidates right now that are focused on raising the mucosal response. Researchers caution that while the body’s spider-web mechanism has the potential to be hugely beneficial, it can cause harm too, including inflammation and further illness when the web formation is uncontrollable…read more. Open Access TECHNICAL ARTICLEÂ