Bacterial nanopores open the future of data storage

Nanowerk  December 14, 2020
The recent development of polymers that can store information at the molecular level has opened new opportunities for ultrahigh density data storage, long-term archival, anticounterfeiting systems, and molecular cryptography. However, synthetic informational polymers are so far only deciphered by tandem mass spectrometry. In comparison, nanopore technology can be faster, cheaper, nondestructive and provide detection at the single-molecule level; moreover, it can be massively parallelized and miniaturized in portable devices. An international team of researchers (Switzerland, France, Brazil) has demonstrated the ability of engineered aerolysin nanopores to accurately read, with single-bit resolution, the digital information encoded in tailored informational polymers alone and in mixed samples, without compromising information density. These findings open promising possibilities to develop writing-reading technologies to process digital data using a biological-inspired platform…read more. Open Access TECHNICAL ARTICLE 

Effects of terminal nucleobases on polymer reading. Credit: Science Advances 09 Dec 2020: Vol. 6, no. 50, eabc2661

 

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