Nanowerk April 20, 2020
Label-free contrasts of Quantitative phase imaging (QPI) and molecular vibrational imaging (MVI) are inherently complementary and difficult to integrate due to their reliance on different light–matter interactions. Researchers in Japan present a unified imaging scheme with simultaneous and in situ acquisition of quantitative phase and molecular vibrational contrasts of single cells in the QPI framework using the mid-infrared photothermal effect. The research may enable new analyses, especially for studying complex and fragile biological phenomena such as drug delivery, cellular disease, and stem cell development…read more. Open Access TECHNICA L ARTICLE
Concept of MV-QPI. (a) Principle of the MV-contrast acquisition in the QPI framework. Credit: Optica Vol. 7, Issue 4, pp. 359-366 (2020)