EurelAlert July 15, 2019
Researchers in Belgium successfully applied Nanobodies® – small antibody fragments – to control the assembly of the bacterial armor and study its structure. The Nanobodies were not only effective in preventing the armor from forming, but also proved highly efficient in breaking down existing S-layers. When applied to live bacteria, breaking down the armor slowed bacterial growth and led to drastic changes in the surface of the bacterial cell. Nanobodies were tested as a treatment in mice infected with B. anthracis. All treated mice recovered from lethal anthrax within days…read more. TECHNICAL ARTICLE