Phys.org  September 1, 2022 The creation of proteins that use specific, sensitive, real-time biological recognition detection methods for VX neurotoxin using directed evolution or library screening methods has been hampered because its toxicity makes laboratory experimentation extraordinarily expensive. A team of researchers in the US (the City College of New York, the State University of New Jersey, Clarkson University) designed the protein to have a cavity at its center that matched the precise shape and chemical composition of VX. The protein underwent a dramatic shape change, burying VX in the cavity. The shape change is the signal which could be […]