Research team follows nearly 8,000 paths towards better cell factories

Phys.org  April 26, 2022 The inhibitory compounds found in hydrolysates in biomass substantially influence the performance of a cell factory and the economic feasibility of lignocellulosic biofuels and chemicals. Researchers in Sweden analyzed data on Saccharomyces cerevisiae mutants engineered for altered tolerance towards the most common inhibitors found in lignocellulosic hydrolysates: acetic acid, formic acid, furans, and phenolic compounds. The mutants included in the analysis had been shown to display increased or decreased tolerance to individual inhibitors or combinations of inhibitors found in lignocellulosic hydrolysates. Genetic engineering aimed at improving inhibitor or hydrolysate tolerance altered the specific growth rate or […]

Engineering a Way Out of Climate Change: Genetically Modified Organisms Could be the Key

Technology.org  November 17, 2020 An international team of researchers (USA – Boston University, UC Santa Barbara, industry, DOE, UC Berkeley, Harvard Medical School, Arizona State University, University of Washington, Woods Hole, Colorado State University, MIT, Cornell University, Oak Ridge National Laboratory, Israel) has identified the possible ways in which synthetic and systems biology (SSB) could be used to reduce greenhouse gas. According to the researchers the range of possibilities include: Engineer plants to reduce atmospheric CO2, Identify genes that control the distribution of Biomass, Genetically modify the Root-to-Shoot ratio of Plants, Engineer plants to increase productivity, Engineer plants to Self-Fertilize, […]