Phys.org September 26, 2023 Rapid, sensitive detection of biomolecules is important for biosensing of infectious pathogens as well as biomarkers and pollutants. Researchers in Japan have achieved rapid and sensitive detection of SARS-CoV-2 nucleocapsid protein antigen by enhancing the performance of optical biosensing based on optical frequency combs (OFC). The virus-concentration-dependent optical spectrum shift produced by antigen–antibody interactions was transformed into a photonic RF shift by a frequency conversion between the optical and RF regions in the OFC, facilitating rapid and sensitive detection with well-established electrical frequency measurements. The active-dummy temperature-drift compensation with a dual-comb configuration enabled the very small […]
Tag Archives: Optical combs
Development of magneto-optic effect measurement device using dual-comb spectroscopy
Phys.org November 19, 2019 Researchers in Japan developed a desktop prototype magneto-optic effect measurement device capable of evaluating the characteristics of magnetic materials with improved optical system and signal detection system its measurement performance greatly exceeds conventional measurement methods. It has magneto-optic effect measurement resolution of 0.01 degree, a wavelength resolution of 0.01 nanometer and capable of high-speed measurement through batch measurements of all wavelength components. A major feature of the prototype is its capability to measure the phase difference of light in addition to its intensity ratio. It is expected to become an important new tool for the precise […]