SciTech Daily  August 8, 2021 The replication transcription complex (RTC) from the virus SARS-CoV-2 is responsible for recognizing and processing RNA for two principal purposes, propagation into new virus and for ribosomal transcription of viral proteins. The RTC will discontinuously transcribe specific sections of viral RNA to amplify certain proteins over others. A team of researchers in the US (University of Chicago, Lawrence Berkeley National Laboratory, Berkeley, Oak Ridge National Laboratory, University of Auburn) has conducted a systematic structural investigation of three components that make up the RTC: Nsp7, Nsp8, and Nsp12 and solved high-resolution crystal structures of the Nsp7/8 […]