Novel microfluidic chip can detect contaminants in 100-picoliter samples

Nanowerk  June 27, 2022 Researchers in Japan have developed a nonlinear optical crystal-based compact terahertz (THz)-microfluidic chip with several I-design meta-atoms for attomole (amol)-level sensing of trace amounts of solution samples. The chip consists of a metallic strip with a micrometer-sized gap sandwiched by other metallic strips. A point THz source locally generated by optical rectification at the irradiation spot of a femtosecond-pulse laser beam induced a tightly confined electric-field mode at the gap regions and modified the resonance frequency when a microchannel fabricated along the space between the metallic strips was filled with solutions. Using this chip, they could […]