Phys.org  April 20, 2022 An international team of researchers (China, UK) studied antimicrobial resistance gene overlap between E. coli isolates collected from humans, livestock and their shared environments in a large-scale Chinese poultry farm and associated slaughterhouse. By using a computational approach that integrates machine learning, whole-genome sequencing, gene sharing network and mobile genetic elements analysis they characterized the E. coli community structure, antimicrobial resistance phenotypes and the genetic relatedness of non-pathogenic and pathogenic E. coli strains. They uncovered the network of genes, associated with antimicrobial resistance (AMR), shared across host species (animals and workers) and environments (farm and slaughterhouse). […]