Nanowerk October 22, 2022 Bottom-up engineering of synthetic condensates advances our understanding of the organizing principle of condensates. It also enables the synthesis of artificial systems with novel functions. However, building synthetic condensates with a predictable organization and function remains challenging. Researchers in South Korea used DNA as a building block to create synthetic condensates that are assembled through phase separation. The programmability of intermolecular interactions between DNA molecules enabled the control over various condensate properties including assembly, composition, and function. Similar to the way intracellular condensates are organized, DNA clients were selectively partitioned into cognate condensates. They demonstrated how […]
Tag Archives: DNA computation
DNA computer using glass beads increases parallel processing power
Phys.org March 29, 2022 In general, DNA computation conducted in individual tubes is slow in generating chemical outputs in response to chemical inputs and requires fluorescence readout. Researchers at Emory University have introduced a new paradigm for DNA computation where the chemical input is processed and transduced into a mechanical output using dynamic DNA-based motors operating far from equilibrium. They applied DNA as a coating to extremely small glass beads. In practice, the glass beads either roll across the surface of a base of gold or hold steady, depending on how the DNA coating interacts with molecules that have been […]