Phys.org  April 26, 2022 The inhibitory compounds found in hydrolysates in biomass substantially influence the performance of a cell factory and the economic feasibility of lignocellulosic biofuels and chemicals. Researchers in Sweden analyzed data on Saccharomyces cerevisiae mutants engineered for altered tolerance towards the most common inhibitors found in lignocellulosic hydrolysates: acetic acid, formic acid, furans, and phenolic compounds. The mutants included in the analysis had been shown to display increased or decreased tolerance to individual inhibitors or combinations of inhibitors found in lignocellulosic hydrolysates. Genetic engineering aimed at improving inhibitor or hydrolysate tolerance altered the specific growth rate or […]