Phys.org  March 31, 2022 The development of hydrogel-based 4D bioinks, especially those allowing living cell printing, with easy preparation, defined composition, and controlled physical properties is critically important for 4D bioprinting. Researchers at the University of Illinois have developed a single-component jammed micro-flake hydrogel (MFH) system with heterogeneous size distribution, which differs from the conventional granular microgel as a new cell-laden bioink for 4D bioprinting. The cytocompatible MFH features scalable production and straightforward composition with shear-thinning, shear-yielding, and rapid self-healing properties. It can be smoothly printed into stable 3D bioconstructs, which can be further cross-linked to form a gradient in […]