Phys.org  July 22, 2024 A team of researchers in the US (Virginia Polytechnic and State University, Edward Via College of Osteopathic Medicine, LA) discovered a significant correlation between pupal abnormalities and the feminization of subsequent adults exemplified by the relative abundance of ovarian and testicular tissues. All intersex individuals were genetic males as they expressed a male determining factor, Nix. The presence of both male and female splice variants indicated that sex determination was disrupted. Intersexes had largely normal gene expression in testes but significant gene downregulation in male accessory glands when compared with normal males. They concluded that evolving […]