Scientists develop novel DNA logic circuits

Phys.org  July 12, 2021 To construct a bipedal DNA walking nanomachine an international team of researchers (USA – University of New York, China) constructed a series of DNA logic circuits based on cascade strand displacement amplification. They modified track DNA probes with the stem-loop structure on the electrode interface. In the upstream homogeneous system, target-triggered strand displacement amplification was introduced to generate a large number of single-stranded sequences. The DNA three-way junction structure was then assembled as a bipedal moved around the electrode interface to enrich electrochemical signal molecules. Using incomplete three-way junction and double-stranded structures, logic gates AND and […]